Level of inflammatory markers in patients and controls
| Control | DLB | AD | MCI-LB | MCI-AD | |
| CRP, mg/mL | 3.35±5.72 | 1.73±2.12 | 6.29±14.56 | 4.12±6.44 | 3.41±3.34 |
| IFN-gamma, pg/L | 7.56±6.13 | 5.13±4.13 | 9.01±12.06 | 6.52±4.30 | 8.75±12.08 |
| IL-10, pg/L | 0.46±0.62 | 0.43±0.52 | 0.60±0.75 | 0.96±0.54*†‡ | 0.93±0.36*†‡ |
| IL-1beta, pg/L | 0.51±2.16 | 0.07±0.33 | 0.03±0.08 | 1.92±1.24*†‡ | 2.72±1.51*†‡ |
| IL-2, pg/L | 0.38±0.42 | 0.34±0.37 | 0.39±0.68 | 3.68±0.85*†‡ | 3.56±0.92*†‡ |
| IL-4, pg/L | 0.03±0.05 | 0.02±0.03 | 0.01±0.03 | 0.80±0.16*†‡ | 0.85±0.21*†‡ |
| IL-6, pg/l | 1.66±0.99 | 2.02±2.00 | 2.78±2.21 | 2.90±10.39 | 3.32±4.34 |
| IL-8, pg/L | 4.85±1.49 | 5.10±2.03 | 5.11±2.25 | 6.75±17.50 | 4.34±2.88 |
| TNF-alpha, pg/L | 4.26±1.32 | 4.02±1.61 | 4.28±2.38 | 2.23±2.01*†‡ | 3.08±3.53*† |
Results are presented as mean±SD.
*Significantly different from controls (P≤0.001).
†Significantly different from DLB group (P≤0.001).
‡Significantly different from AD group (P≤0.001).
AD, Alzheimer’s disease; CRP, C reactive protein; DLB, dementia with Lewy bodies; IFN-gamma, interferon-gamma; IL, interleukin; MCI, mild cognitive impairment; MCI-AD, MCI with probable Alzheimer’s disease; MCI-LB, MCI with probable Lewy body dementia; TNF-alpha, tumour necrosis factor-alpha.